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In a Phase 2a trial specifically evaluating liver outcomes, retatrutide achieved an average 82% reduction in liver fat content

PLOS ONE 6 , e22652 (2011)

The day of weekly administration can be changed, if necessary, as long as the time between the 2 doses is at least 3 days (72 hours)

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Frequency: Once to twice weekly for maintenance, or more frequently during deficiency correction